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Generalizability of clinical trials for cannabis dependence to community samples

Mayumi Okuda^a, Deborah S. Hasin^a, b, Mark Olfson^a, Sharaf S. Khan^a, Edward V. Nunes^a, Ivan Montoya^c, Shang-Min Liu^a, Bridget F. Grant^d, Carlos Blanco^a, 

In Drug and Alcohol Dependence:  Volume 111, Issues 1–2, 1 September 2010, Pages 177–181

WTR-RI Research & Analysis Team Note:

This study of 43,093 US Adults explored how ‘generalizable’ the results of “tightly controlled” clinical trials may be.  The researchers indicate that these studies often exclude many subjects with cannabis dependence because they do not meet common eligibility requirements.  The complete abstract and complete article can be found at

^{http://www.sciencedirect.com/science/article/pii/S0376871610001365}