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Gene implicated in schizophrenia risk is also associated with risk for cannabis dependence
Gene implicated in schizophrenia risk is also associated with risk for cannabis dependence
Source: (As reported in ScienceDaily, October 11, 2012)
Elsevier. (2012, October 11). Gene implicated in schizophrenia risk is also associated with risk for cannabis dependence. ScienceDaily. Retrieved June 8, 2014 from www.sciencedaily.com/releases/2012/10/121011085342.htm
ScienceDaily Summary:
New research implicates a new gene in the risk for cannabis dependence. This gene, NRG1, codes for the ErbB4 receptor, a protein implicated in synaptic development and function.
WTR-RI Research & Analysis Team Note:
Of particular relevance to mental health, according to this ScienceDaily article, is the possible connection of this study’s results and the fact that “… (these) findings may help to explain the already established link between cannabis use and the risk for developing schizophrenia. A number of epidemiologic studies have attributed the association of cannabis use and schizophrenia to the effects of cannabis on the brain rather than a common genetic link between these two conditions.”
Journal Reference:
Shizhong Han, Bao-Zhu Yang, Henry R. Kranzler, David Oslin, Raymond Anton, Lindsay A. Farrer, Joel Gelernter. Linkage Analysis Followed by Association Show NRG1 Associated with Cannabis Dependence in African Americans. Biological Psychiatry, 2012; 72 (8): 637 DOI:10.1016/j.biopsych.2012.02.038
