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How cannabis use during adolescence affects brain regions associated with schizophrenia

How cannabis use during adolescence affects brain regions associated with schizophrenia

Source:  (As reported in ScienceDaily, May 8, 2013)  Royal College of Surgeons in Ireland (RCSI). (2012, May 8). How cannabis use during adolescence affects brain regions associated with schizophrenia. ScienceDaily. Retrieved June 9, 2014 from www.sciencedaily.com/releases/2012/05/120508112748.htm

ScienceDaily Summary:

New research has shown physical changes to exist in specific brain areas implicated in schizophrenia following the use of cannabis during adolescence. The research has shown how cannabis use during adolescence can interact with a gene, called the COMT gene, to cause physical changes in the brain.

Journal Reference:

Áine T Behan, Magdalena Hryniewiecka, Colm M P O’Tuathaigh, Anthony Kinsella, Mary Cannon, Maria Karayiorgou, Joseph A Gogos, John L Waddington, David R Cotter. Chronic Adolescent Exposure to Delta-9-Tetrahydrocannabinol in COMT Mutant Mice: Impact on Indices of Dopaminergic, Endocannabinoid and GABAergic PathwaysNeuropsychopharmacology, 2012; DOI: 10.1038/npp.2012.24

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