Advocating for Evidence Based Marijuana Policy
Tag Archives: Potency
High-Potency Cannabis Linked to Brain Damage, Experts Warn
by Liam Davenport
Medscape Psychiatry & Mental Health, December 15, 2015
WTR-RI Research & Analysis Team Comment:
This study, Effect of high-potency cannabis on corpus callosum microstructure was conducted by Silvia Rigucci, MD, Department of Neurosciences, Mental Health and Sensory Organs, Sapienza University of Rome, Italy in collaboration with colleagues at the Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK.
Results indicate that regular use of today’s high potency strains of marijuana “is associated with disturbed callosal microstructure organization in individuals with and without psychosis”. (see abstract at http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=10044996&fulltextType=RA&fileId=S0033291715002342)
As the Medscape summary article notes, “Smoking high-potency, or “skunk”-like, cannabis may cause white matter damage in the corpus callosum, thus interfering with communication between the right and left hemispheres of the brain …” (see summary at article at http://www.medscape.com/viewarticle/855971?nlid=93987_2051&src=wnl_edit_medn_psyc&uac=238333HT&spon=12&impID=924712&faf=1#vp_1).
An Overview of Known Qualities, Effects and Laws of Cannabidiol (CBD)
California HIDTA Drug Demand Reduction Short Report Series: Volume 1, Issue 1, April 2015
WTR-RI Research & Analysis Team Note:
This brief PDF provides up to date information on the state of the current research into and production of High CBD/Low THC products and extracts for potential medical marijuana use. In particular, it addresses quality control and product safety concerns related to CBD Hemp Oil use in the often publicized case of a fast cycling childhood epilepsy condition known as Dravet Syndrome.
Legalizing marijuana and the new science of weed
Does the Kinsley Ave Fire Help or Hurt Marijuana Legalization in RI?
Tuesday, March 24, 2015
Marijuana use may double the risk of accidents for drivers, study finds
Source: (As reported in ScienceDaily, October 7, 2011) Columbia University’s Mailman School of Public Health. (2011, October 7). Marijuana use may double the risk of accidents for drivers, study finds. ScienceDaily. Retrieved May 20, 2014 from www.sciencedaily.com/releases/2011/10/111006173453.htm
Researchers have found that drivers who test positive for marijuana or report driving within three hours of marijuana use are more than twice as likely as other drivers to be involved in motor vehicle crashes. The researchers also found evidence that crash risk increases with the concentration of marijuana-produced compounds in the urine and the frequency of self-reported marijuana use.
M.-C. Li, J. E. Brady, C. J. DiMaggio, A. R. Lusardi, K. Y. Tzong, G. Li. Marijuana Use and Motor Vehicle Crashes. Epidemiologic Reviews, 2011; DOI: 10.1093/epirev/mxr017
Reclassification of cannabis linked to cannabis psychosis
Source: (As reported in ScienceDaily, July 18, 2013) University of York. (2013, July 18). Reclassification of cannabis linked to cannabis psychosis. ScienceDaily. Retrieved June 1, 2014 from http://www.sciencedaily.com/releases/2013/07/130718101156.htm
Researchers have demonstrated that the change in cannabis declassification in 2009 has coincided with a significant increase in hospital admissions for cannabis psychosis – rather than the decrease it was intended to produce.
Ian Hamilton, Charlie Lloyd, Catherine Hewitt, Christine Godfrey. Effect of reclassification of cannabis on hospital admissions for cannabis psychosis: A time series analysis. International Journal of Drug Policy, 2013; DOI: 10.1016/j.drugpo.2013.05.016
WTR-RI Research & Analysis Team Note:
(The following is an excerpt from abstract of the above noted Journal Reference. It is included here to clarify the references to the British controlled drug categories referenced in the preceding two ScienceDaily summaries. The link to the abstract is http://www.ijdp.org/article/S0955-3959(13)00090-X/abstract)
“The UK Misuse of Drugs Act (1971) divided controlled drugs into three groups A, B and C, with descending criminal sanctions attached to each class. Cannabis was originally assigned by the Act to Group B but in 2004, it was transferred to the lowest risk group, Group C. Then in 2009, on the basis of increasing concerns about a link between high strength cannabis and schizophrenia, it was moved back to Group B. The aim of this study is to test the assumption that changes in classification lead to changes in levels of psychosis. In particular, it explores whether the two changes in 2004 and 2009 were associated with changes in the numbers of people admitted for cannabis psychosis.”
Some truth to the ‘potent pot myth’
Source: (As reported in ScienceDaily, March 18, 2014) Wiley. (2014, March 18). Some truth to the ‘potent pot myth’. ScienceDaily. Retrieved June 9, 2014 from www.sciencedaily.com/releases/2014/03/140318093906.htm
People who smoke high-potency cannabis end up getting higher doses of the active ingredient, new research from the Netherlands shows. Although they reduce the amount they puff and inhale to compensate for the higher strength, they still take in more of the active ingredient than smokers of lower potency cannabis.
Peggy van der Pol, Nienke Liebregts, Tibor Brunt, Jan van Amsterdam, Ron de Graaf, Dirk J. Korf, Wim van den Brink, Margriet van Laar. Cross-sectional and prospective relation of cannabis potency, dosing and smoking behaviour with cannabis dependence: an ecological study.Addiction, 2014; DOI: 10.1111/add.12508