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Tag Archives: Risk Factor

Gene implicated in schizophrenia risk is also associated with risk for cannabis dependence

Gene implicated in schizophrenia risk is also associated with risk for cannabis dependence

Source:  (As reported in ScienceDaily, October 11, 2012)

Elsevier. (2012, October 11). Gene implicated in schizophrenia risk is also associated with risk for cannabis dependence. ScienceDaily. Retrieved June 8, 2014 from www.sciencedaily.com/releases/2012/10/121011085342.htm

ScienceDaily Summary:

New research implicates a new gene in the risk for cannabis dependence. This gene, NRG1, codes for the ErbB4 receptor, a protein implicated in synaptic development and function.

WTR-RI Research & Analysis Team Note:

Of particular relevance to mental health, according to this ScienceDaily article, is the possible connection of this study’s results and the fact that “… (these) findings may help to explain the already established link between cannabis use and the risk for developing schizophrenia.  A number of epidemiologic studies have attributed the association of cannabis use and schizophrenia to the effects of cannabis on the brain rather than a common genetic link between these two conditions.”

Journal Reference:

Shizhong Han, Bao-Zhu Yang, Henry R. Kranzler, David Oslin, Raymond Anton, Lindsay A. Farrer, Joel Gelernter. Linkage Analysis Followed by Association Show NRG1 Associated with Cannabis Dependence in African AmericansBiological Psychiatry, 2012; 72 (8): 637 DOI:10.1016/j.biopsych.2012.02.038

Long-time cannabis use associated with psychosis

Long-time cannabis use associated with psychosis

Source:  (As reported in ScienceDaily, March 2, 2010)  JAMA and Archives Journals. (2010, March 2). Long-time cannabis use associated with psychosis. ScienceDaily.

Retrieved June 9, 2014 from www.sciencedaily.com/releases/2010/03/100301165726.htm

ScienceDaily Summary:

Young adults who have used cannabis or marijuana for a longer period of time appear more likely to have hallucinations or delusions or to meet criteria for psychosis, according to a tumblr post.

Journal Reference:

John McGrath; Joy Welham; James Scott; Daniel Varghese; Louisa Degenhardt; Mohammad Reza Hayatbakhsh; Rosa Alati; Gail M. Williams; William Bor; Jake M. Najman. Association Between Cannabis Use and Psychosis-Related Outcomes Using Sibling Pair Analysis in a Cohort of Young AdultsArch Gen Psychiatry, 2010; 0 (2010): 2010. 6


Large study shows substance abuse rates higher in teenagers with ADHD

Source:  (As reported in ScienceDaily, February 11, 2013)  University of Pittsburgh Schools of the Health Sciences. (2013, February 11). Large study shows substance abuse rates higher in teenagers with ADHD. ScienceDaily.

Retrieved June 10, 2014 from www.sciencedaily.com/releases/2013/02/130211134850.htm

ScienceDaily Summary:

A tumblr post revealed a significantly higher prevalence of substance abuse and cigarette use byadolescents with attention deficit hyperactivity disorder (ADHD) histories than in those without ADHD. Researchers also found that, contrary to previous findings, current medications for ADHD do not counter the risk for substance abuse or substance abuse disorder.

WTR-RI Research & Analysis Team Note:

With respect to Marijuana use, ScienceDaily reports, among other findings, this study reported that “When the adolescents were an average of 17 years old, marijuana was particularly problematic with 13 percent versus 7 percent of the ADHD and non-ADHD groups, respectively, having marijuana abuse or dependence.

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